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Subject
Liver Diseases -- Path... (63)
Pathology (63)
Liver (63)

Creator
Musc Department of Pat... (63)

Date
1900-1999 (62)
20th C (1)

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The Gordon R. Hennigar Pathology Museum Collection

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21.
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Liver: Nodular Hyperplasia
Liver: Nodular Hyperplasia Nodular hyperplasia of liver. COMMENT: #46 and #48 have well developed scars in the presence of nodular liver tissue, these being the gross characteristics of this lesion (review microscopic characteristics).
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Liver: Multiple Adenomas
Liver: Multiple Adenomas Multiple liver cell adenomas . COMMENT(#49 & #50): Good examples of multiple adenomas; areas of infarction/hemorrhage often found (remember microscopic characteristics).
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Liver: Cirrhosis
Liver: Cirrhosis Finely and coarsely nodular cirrhosis of liver (mucoviscidosis sequelae). COMMENT (#40-#41): Although a finely nodular biliary cirrhosis is described, one can also see a coarsely nodular (macronodular) pattern in the livers of longstanding cystic fibrosis
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Liver: Fatal Intraperitoneal Hemorrhage
Liver: Fatal Intraperitoneal Hemorrhage Fatal intraperitoneal hemorrhage following needle biopsy of normal liver. Comment: Note needle tract and subcapsular hemorrhage.
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Liver: Gunshot Wound with Hemorrhage and Necrosis
Liver: Gunshot Wound with Hemorrhage and Necrosis GSW of liver with hemorrhage and necrosis
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Liver: Alcoholic Cirrhosis
Liver: Alcoholic Cirrhosis Portal cirrhosis; fatty degeneration. COMMENT: Specimens 13-22 are all examples of cirrhosis associated with alcoholism (Laennec's, portal, nutritional, alcoholic)--note that the specimens have a micronodular pattern in general with a generally uniform appearance to the nodules; however, note that some of the livers have nodules of up to about 1 cm. (see note below) and that there may be some variability in nodule size within one specimen. Intervening parenchyma is composed of fibrous septae. Also note that the remaining nodular liver parenchyma is quite pale or yellow = fatty change associated with continued alcohol abuse. Picture corresponding microscopic picture in your mind's eye of fatty change and cirrhosis (remember the definition of cirrhosis). Specimen #22 indicates that microscopically there is necrosis of hepatocytes with an inflammatory response = this is not evident grossly in this specimen. In this series, the small firm livers are good examples of end stage nutritional or alcoholic cirrhosis. NOTE: Although Robbins says that micronodular cirrhosis has nodules of up to 1 cm. in diameter, Dr. Hennigar's measurement of 3mm. and below is more characteristic.
27.
Liver: Alcoholic Cirrhosis
Liver: Alcoholic Cirrhosis Alcoholic cirrhosis . COMMENT: Specimens 13-22 are all examples of cirrhosis associated with alcoholism (Laennec's, portal, nutritional, alcoholic)--note that the specimens have a micronodular pattern in general with a generally uniform appearance to the nodules; however, note that some of the livers have nodules of up to about 1 cm. (see note below) and that there may be some variability in nodule size within one specimen. Intervening parenchyma is composed of fibrous septae. Also note that the remaining nodular liver parenchyma is quite pale or yellow = fatty change associated with continued alcohol abuse. Picture corresponding microscopic picture in your mind's eye of fatty change and cirrhosis (remember the definition of cirrhosis). Specimen #22 indicates that microscopically there is necrosis of hepatocytes with an inflammatory response = this is not evident grossly in this specimen. In this series, the small firm livers are good examples of end stage nutritional or alcoholic cirrhosis. NOTE: Although Robbins says that micronodular cirrhosis has nodules of up to 1 cm. in diameter, Dr. Hennigar's measurement of 3mm. and below is more characteristic.
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Liver: Acute Passive Congestion
Liver: Acute Passive Congestion Acute passive congestion of liver. Comment: Darker red areas particularly show a nutmeg pattern
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Liver: Primary Hepatoma--Cholangiocarcinoma
Liver: Primary Hepatoma--Cholangiocarcinoma Primary hepatoma--cholangiocarcinoma. COMMENT: Good portion of specimen occupied by solid white tumor (arrow) infiltrating liver
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Liver: Cholangiocarcinoma
Liver: Cholangiocarcinoma Cholangiocarcinoma. COMMENT: Diffuse involvement by tumor (Green = ""normal"" liver)--small areas of infarct also present (arrows)
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Liver: Cholangiocarcinoma
Liver: Cholangiocarcinoma Cholangiocarcinoma and metastatic oat cell carcinoma in liver. COMMENT: Central carved-out area represents focus of cholangiocarcinoma; nodular areas=metastatic oat cell (lung) tumor (A81-512)
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Liver: Laennec's Cirrhosis
Liver: Laennec's Cirrhosis Laennec's cirrhosis . COMMENT: Specimens 13-22 are all examples of cirrhosis associated with alcoholism (Laennec's, portal, nutritional, alcoholic)--note that the specimens have a micronodular pattern in general with a generally uniform appearance to the nodules; however, note that some of the livers have nodules of up to about 1 cm. (see note below) and that there may be some variability in nodule size within one specimen. Intervening parenchyma is composed of fibrous septae. Also note that the remaining nodular liver parenchyma is quite pale or yellow = fatty change associated with continued alcohol abuse. Picture corresponding microscopic picture in your mind's eye of fatty change and cirrhosis (remember the definition of cirrhosis). Specimen #22 indicates that microscopically there is necrosis of hepatocytes with an inflammatory response = this is not evident grossly in this specimen. In this series, the small firm livers are good examples of end stage nutritional or alcoholic cirrhosis. NOTE: Although Robbins says that micronodular cirrhosis has nodules of up to 1 cm. in diameter, Dr. Hennigar's measurement of 3mm. and below is more characteristic.
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Liver: Metastatic Ovarian Carcinoid
Liver: Metastatic Ovarian Carcinoid Ovarian carcinoid metastatic to liver
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Liver: Laennec's Cirrhosis
Liver: Laennec's Cirrhosis Laennec's cirrhosis. COMMENT: Specimens 13-22 are all examples of cirrhosis associated with alcoholism (Laennec's, portal, nutritional, alcoholic)--note that the specimens have a micronodular pattern in general with a generally uniform appearance to the nodules; however, note that some of the livers have nodules of up to about 1 cm. (see note below) and that there may be some variability in nodule size within one specimen. Intervening parenchyma is composed of fibrous septae. Also note that the remaining nodular liver parenchyma is quite pale or yellow = fatty change associated with continued alcohol abuse. Picture corresponding microscopic picture in your mind's eye of fatty change and cirrhosis (remember the definition of cirrhosis). Specimen #22 indicates that microscopically there is necrosis of hepatocytes with an inflammatory response = this is not evident grossly in this specimen. In this series, the small firm livers are good examples of end stage nutritional or alcoholic cirrhosis. NOTE: Although Robbins says that micronodular cirrhosis has nodules of up to 1 cm. in diameter, Dr. Hennigar's measurement of 3mm. and below is more characteristic.
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Liver: Metastatic Choriocarcinoma
Liver: Metastatic Choriocarcinoma Metastatic choriocarcinoma; multifaceted pigment stones in gallbladder. COMMENT (#60-64): Metastatic tumors in liver characteristically have central necrosis (umbilicated appearance through the capsule) due to outgrowth of blood/nutrient supply--other than this, variations in appearance may reflect origin of tumor i.e., the melanoma is represented by both pigmented and non-pigmented (amelanotic) metastases; choriocarcinoma typically is hemorrhagic. The cholelithiasis in #64 is unrelated to metastatic tumor)
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Liver: Laceration
Liver: Laceration Laceration of liver
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Liver: Laennec's Cirrhosis
Liver: Laennec's Cirrhosis Laennec's cirrhosis. COMMENT: Specimens 13-22 are all examples of cirrhosis associated with alcoholism (Laennec's, portal, nutritional, alcoholic)--note that the specimens have a micronodular pattern in general with a generally uniform appearance to the nodules; however, note that some of the livers have nodules of up to about 1 cm. (see note below) and that there may be some variability in nodule size within one specimen. Intervening parenchyma is composed of fibrous septae. Also note that the remaining nodular liver parenchyma is quite pale or yellow = fatty change associated with continued alcohol abuse. Picture corresponding microscopic picture in your mind's eye of fatty change and cirrhosis (remember the definition of cirrhosis). Specimen #22 indicates that microscopically there is necrosis of hepatocytes with an inflammatory response = this is not evident grossly in this specimen. In this series, the small firm livers are good examples of end stage nutritional or alcoholic cirrhosis. NOTE: Although Robbins says that micronodular cirrhosis has nodules of up to 1 cm. in diameter, Dr. Hennigar's measurement of 3mm. and below is more characteristic.
38.
Liver: Multiple Infarction, Ischemic Heart Disease
Liver: Multiple Infarction, Ischemic Heart Disease Multiple infarction of liver--ischemic heart disease. Comment: Multifocal areas of infarction are present--easiest to see are white, sharply demarcated, with irregular borders.
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Liver: Multiple Adenomas
Liver: Multiple Adenomas Multiple liver cell adenomas. COMMENT(#49 & #50): Good examples of multiple adenomas; areas of infarction/hemorrhage often found (remember microscopic characteristics).
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Liver: Laennec's Cirrhosis
Liver: Laennec's Cirrhosis Laennec's cirrhosis (severe). COMMENT: Specimens 13-22 are all examples of cirrhosis associated with alcoholism (Laennec's, portal, nutritional, alcoholic)--note that the specimens have a micronodular pattern in general with a generally uniform appearance to the nodules; however, note that some of the livers have nodules of up to about 1 cm. (see note below) and that there may be some variability in nodule size within one specimen. Intervening parenchyma is composed of fibrous septae. Also note that the remaining nodular liver parenchyma is quite pale or yellow = fatty change associated with continued alcohol abuse. Picture corresponding microscopic picture in your mind's eye of fatty change and cirrhosis (remember the definition of cirrhosis). Specimen #22 indicates that microscopically there is necrosis of hepatocytes with an inflammatory response = this is not evident grossly in this specimen. In this series, the small firm livers are good examples of end stage nutritional or alcoholic cirrhosis. NOTE: Although Robbins says that micronodular cirrhosis has nodules of up to 1 cm. in diameter, Dr. Hennigar's measurement of 3mm. and below is more characteristic.