This letter, from Fred Garrissen of Bremen, Germany to William Stephen, a Charleston merchant, concerns Atlantic shipping interests in the late-18th century. Garrissen explains that there were major food shortages in Germany and informs Stephen that Europeans were dependent on trade from the Americas. Garrissen asked Stephen to send him "old rice," tobacco, coffee, pimento, cotton, deerskins, and sugar so that he can resell the materials for a large profit.
A collection consisting of two letters discussing smallpox vaccinations sent from Dr. John Vaughan of Philadelphia to Dr. Philip Tidyman of Charleston, S.C. The letters are dated December 11, 1801 and April 7, 1802 and the latter contains a sketch of a water filtration system.